Job description

PharmaBiome AG is a pioneer in the development and production of live biotherapeutic products to address disturbances of the gut microbiome. We were founded in Zurich in 2015 as an ETH spin-off at the intersection of microbiology, biotechnology, and data science. We believe that the future of microbiome-based therapeutics lies in the development of the biotechnology necessary to produce human medicines. This holds the promise of becoming a first step in the creation of treatments for patients with chronic inflammatory diseases, immune conditions, and special nutritional needs.

We are currently seeking a qualified, highly motivated, experienced individual for an open position located in Schlieren (Zurich, Switzerland).

Senior Quantitative Microbiome Scientist (80-100%)


We are seeking a Senior Quantitative Microbiome Scientist as a member of PharmaBiome’s Research and Development team. The successful applicant will take on the responsibilities of analyzing biological data, and reporting and interpreting the results to advance PharmaBiome’s R&D programs. PharmaBiome’s R&D activities span microbiome research in the broadest sense, including microbiology, chemical analytics, biotechnology, and computational biology. The results of this work directly contribute to the development of current and future assets and inform the scientific strategy of the company. This position is critical to PharmaBiome’s vision and business activities. This is an exciting opportunity for a microbial ecologist with a strong quantitative background and solid bioinformatic skills.

Your responsibilities:

  • Hypothesis-driven analysis and interpretation of microbiome data from in vitro and in vivo preclinical experiments, and clinical cohorts
  • Development of mathematically sound predictive statistical / machine learning models that are based on both in-house generated and publicly available biological data
  • Work collaboratively within PharmaBiome’s R&D team focused on consortium design and microbiome biomarker discovery
  • Support the translation of high-level scientific objectives into executable research plans on the team level
  • Maintain detailed technical documentation as appropriate
  • Write and review research reports documenting the results and conclusions for internal circulation and for collaborations with third-parties
  • Development and improvement of existing and new interactive dashboards for scientific data that enable and substantiate scientific discovery in the team
  • Oversee and maintain PharmaBiome’s central data ecosystem, and develop computational analysis tools that interface directly with PharmaBiome’s central data repository

Your skills and competencies:

  • PhD or equivalent in biology, ecology, or other natural science disciplines with a strong quantitative background and >2 yrs experience (industry or academic) with a track record of independent research
  • Hands-on experience in quantitatively analyzing microbiome data
  • Exceptional proactive and creative problem solving
  • Ability to integrate new developments in the workflow and agility to adapt the research plans accordingly
  • Agree to and take on PharmaBiome’s company values: “transparency, ownership, team appreciation, and continuous improvement”
  • Hands-on experience with next-generation sequencing technologies and the analysis of the resulting data (16S amplicon sequencing, metagenomic, metatranscriptomic, etc.)
  • Experience with bioinformatic tools for genomic and statistical analysis (sequence alignment, genome assembly, phylogenetics)
  • High proficiency in relevant programming languages and frameworks for web, database, and bioinformatics, including database technologies
  • Experience in cloud computing, preferably Google Cloud
  • Experience with LIMS/ELNs, in particular, Benchling, is a plus

Would you like to contribute to PharmaBiome? If you are interested, please send your complete application to PharmaBiome AG is an equal-opportunity employer. We offer a diverse, dynamic, and inclusive environment for our employees. We stand by our team and believe that talent, dedication, and effort are the drivers of PharmaBiome’s success. Together, we aim to make the microbiome druggable.

PharmaBiome AG will not accept unsolicited resumes from any source other than directly from a candidate. PharmaBiome AG will not pay a fee related to unsolicited resumes to any agency that does not have a fully-executed service contract in place.


Zürich, Switzerland

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