Research Associate – Downstream processing (DSP)

Anjarium is a privately held, early-stage biotechnology company focused on creating a new class of non-viral gene therapies to deliver more predictable, enduring, and inclusionary ways to tackle genetic disease throughout a patient’s lifetime. The Company’s versatile platform aims to leverage breakthrough science and expertise at the interface of genetic medicine, synthetic biology and nanoparticle engineering to generate a pipeline of advanced gene therapies with unique competitive advantages over current viral-vector based gene therapies.  We are backed by leading international and strategic investors Abingworth, Gimv, Omega Funds, Pfizer Ventures and Surveyor Capital (a Citadel company).

Currently headquartered at Biotechnopark in Zurich, Switzerland, we are rapidly expanding our teamand are looking for talented and creative individuals, driven by patient outcomes, to join us. Our team is passionate about building a new generation of durable genetic medicines for life-threatening diseases while pushing forward the frontiers of gene therapy.

About the Role
The candidate will join our DSP R&D team and will contribute to developing novel processes, optimizing existing processes and performing periodic bench-scale production tasks to produce and purify our key products ranging from nucleic acids to complex biologics. Responsibilities will include applying statistical approaches for process optimization (DoE), handling of chromatographic equipment (e.g. Äkta and HPLC systems), application of biochemical methods and thorough documentation and presentation of results.

Key responsibilities:

• Work closely with DSP Scientists to design and execute experiments to generate, purify and characterize nucleic acids, and biologics.
• Characterize purified products with state-of-the-art analytical devices (e.g. HPLC)
• Perform multiparametric experiments for process optimization and miniaturization with robotic liquid handling systems
• Perform bench-scale production to support the different teams with products for in-vitro and in-vivo studies
• Work according to established protocols
• Candidate will be expected to thoroughly document performed experiments in our electronic laboratory documentation system and to present findings on a weekly basis during internal team meetings

Qualifications:

• BSc (+3 years experience), MSc Degree in molecular biology, Biochemistry, Bioengineering or related fields (applicants with a PhD will not be considered)
• Hands-on experience with chromatographic techniques and systems, is a requirement
• Experience in producing and purifying proteins and/or nucleic acids
• Confidence to work within a fast-paced working environment
• Self-motivated and pro-active attitude
• Strong collaboration and team working skills
• Strong written and verbal English skills

Submission of unsolicited resumes in advance of an agreement between Anjarium and any external staffing agency or recruiter does not create any implied obligation on the part of Anjarium Biosciences AG.
External staffing agencies or recruiters are requested to not contact Anjarium employees or members of the Board of Directors directly in any attempt to present candidates.

Anjarium Biosciences AG will not accept unsolicited resumes from any source other than candidates themselves for either current or future positions.