Basilea reports presentations of isavuconazole and ceftobiprole data at European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

Isavuconazole at ECCMID 2018

Saturday, 21 April 2018 - 15:30 - 16:30 CEST, Paper Poster Arena

• Visual and spectrophotometric MICs setting of azoles and amphotericin B against Aspergillus fumigatus complex are comparable using EUCAST 9.3.1 methodology - L. J. Marcos-Zambrano, S. Lopez, L. Martin, X. García-Fernández, A. Gómez, E. Bouza Santiago, P. Munoz, P. Escribano, J. Guinea Ortega; Poster P0169

• Antifungal susceptibility to azoles of clinical invasive Spanish Aspergillus fumigatus complex isolates: no sign of resistance at present - L. J. Marcos-Zambrano, S. Lopez, L. Martin, X. García-Fernández, A. Gómez, M. del Carmen Martinez Jimenez, E. Bouza Santiago, P. Munoz, P. Escribano, J. Guinea Ortega; Poster P0170

• Comparison of the MICs obtained by Etest and EUCAST methods for amphotericin B, itraconazole, posaconazole, voriconazole and isavuconazole against clinical isolates of Aspergillus fumigatus - J. Guitard, L. Verdurme, Y. Senghor, M. E. Bougnoux, A. Fekkar, F. Botterel, E. Dannaoui, C. Hennequin; Poster P0175

• Isavuconazole MICs distribution of 20 yeast species involved in human invasive infections - M. Desnos-Ollivier, A. Boullié, O. Lortholary, F. Dromer; Poster P0296

• In vitro pharmacodynamics of isavuconazole, voriconazole, and posaconazole against agents of aspergillosis, mucormycosis, phaeohyphomycosis, fusariosis, and scedosporiosis. - R. Lewis, N. Beyda, N. Albert, D. P. Kontoyiannis; Poster P0297

• Real life use of isavuconazole - F. Vuotto, B.  Hennart, S. Loridant, F. Loeuillet, M. C. Chopin, B. Sendid, S. Alfandari, K. Faure ; Poster P0298

• The cost of treating invasive mould disease with isavuconazole compared with liposomal amphotericin B followed by posaconazole in France - E. Bagshaw, B. Salaun, M. Blackney, J. Posthumus, D. Kuessner; Poster P0303

• Resistance screening of commonly used antimycotics in rare yeast - A. Pérez Hansen, C. Lass-Flörl, M. Lackner; Poster P0306

• Isavuconazole shortens the QTc interval - S. Mellinghoff, M. Bassetti, D. Dörfel, S. Hagel, N. Lehners, A. Plis, E. Schalk, A. Vena, O. A. Cornely; Poster P0308A

Isavuconazole at ECCMID 2018  (continued)

Saturday, 21 April 2018 - 15:30 - 16:30 CEST, Paper Poster Arena

• Antifungal susceptibility of Spanish Candida auris isolates determined by Etest and Sensititre YeastOne - A. Ruiz, M. Fernandez, E. Canton, M. Garrido Jareño, P. Ramirez, J. L. López-Hontangas, J. P. Garcia; Poster 0312

• Septic metastatic complications after Candida auris candidaemia in the first Spanish outbreak setting - M. Tasias, E. Calabuig, M. Montero, F. Blanes, J. Fernandez, A. Ruiz, I. Castro, A. Aleixandre, J. Mollar, J. Pemán, M. Slavert;
  Poster P0315

Sunday, 22 April 2018 - 13:30 - 14:30 CEST, Paper Poster Arena

• Evaluation of gradient strip for antifungal susceptibility testing of isavuconazole and comparators against Mucorales - P. Vidal, E. Dannaoui; Poster P1243

Monday, 23 April 2018 - 14:30 - 15:30 CEST, ePoster Arena 1

• Identification of an isavuconazole dosing regimen for children aged 2-17 years - A. Desai, W. Hope, M. Neely, C. Lademacher, L. Kovanda; ePoster, oral pres. O0795

Tuesday, 24 April 2018; 14:30 - 15:00 CEST, Hall G

• Pro/con debate: Isavuconazole (not amphotericin B) as primary treatment for mucormycosis - O. A. Cornely; Symposium S1070 / Amphotericin B (not isavuconazole) as primary treatment for mucormycosis - F. Lanternier; Symposium S1071

Ceftobiprole at ECCMID 2018

Saturday, 21 April to Tuesday, 24 April 2018, ePoster terminals

• Activity of ceftobiprole and comparators against a collection of teicoplanin- and/or linezolid-resistant coagulase-negative staphylococci isolated from bloodstream infections - M. Coppi, A. Antonelli, G. Baldi, L. Mosconi, A. Santerre Henriksen, F. Arena, T. Giani, G. M.  Rossolini; ePoster E0003

• Activity of ceftobiprole and comparators against European respiratory tract isolates of MSSA and MRSA from 2016 - I. Morrissey, S. De Angelis, S. Magnet, S. Hawser, A. Santerre-Henriksen; ePoster E0006

Saturday, 21 April 2018; 15:30 - 16:30 CEST, Paper Poster Arena

• Ceftobiprole versus vancomycin in treatment of methicillin-resistant Staphylococcus aureus (MRSA) meningitis in an experimental rabbit model - S. Mermer, E. Bolat, T. Turhan, S. Aydemir, H. Sipahi, O. R. Sipahi; Poster P0263

Monday, 23 April 2018; 13:30 - 14:30 CEST, Paper Poster Arena

• In vitro susceptibility testing of cerufoxime, cefixime, cefpodoxime, cefotaxime, ceftaroline, ceftobiprole, linezolid and tedizolid against isolates of Nocardia by using the E-test method - E. Bergeron, F. Vautrin, T.  Durand, F.  Laurent, V. Rodriguez-Nava; Poster P1841

• In vitro activity of tedizolid, dalbavancin and ceftobiprole against Clostridium difficile - D. Binyamin, O. Nitzan, M. Azrad, Z. Hamo, O. Koren, A. Peretz; P1844

Ceftobiprole at ECCMID 2018 (continued)

Tuesday, 24 April 2018; 12:30 - 13:30 CEST, Paper Poster Arena

• In vivo assessment of ceftobiprole versus daptomycin in a murine model of Staphylococcus aureus bacteremia: antimicrobial activity and impact on host inflammatory response - L. Bouard, J. Caillon, V. Le Mabecque, E. Thomas, K. Asehnoune, C. Jacqueline; Poster P2025

• Epidemiology and ceftobiprole susceptibility of European Enterobacteriaceae and Gram-positive clinical isolates from different infection sources collected in 2016 - S. Hawser, S. De Angelis, S. Magnet, I. Morrissey, A. Santerre-Henriksen; Poster P2441

• Bactericidal and synergistic activity of ceftobiprole combined with different antibiotics against selected Gram-positive isolates - F. Campanile, D. Bongiorno, C. Pulitano, S. Stefani; Poster P2498