• Friday, April 20, 2018 @ 12:00 am

Basel, Switzerland, April 20, 2018 - Basilea Pharmaceutica Ltd. (SIX: BSLN) announced today that a broad range of posters and presentations on the antifungal isavuconazole (Cresemba®) and the antibiotic ceftobiprole (Zevtera®) will be presented at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), which will be held in Madrid, Spain, from April 21 to 24, 2018.

The details for the presentations are as follows:

Isavuconazole at ECCMID 2018

Saturday, 21 April 2018 - 15:30 - 16:30 CEST, Paper Poster Arena

  • Visual and spectrophotometric MICs setting of azoles and amphotericin B against Aspergillus fumigatus complex are comparable using EUCAST 9.3.1 methodology - L. J. Marcos-Zambrano, S. Lopez, L. Martin, X. García-Fernández, A. Gómez, E. Bouza Santiago, P. Munoz, P. Escribano, J. Guinea Ortega; Poster P0169

  • Antifungal susceptibility to azoles of clinical invasive Spanish Aspergillus fumigatus complex isolates: no sign of resistance at present - L. J. Marcos-Zambrano, S. Lopez, L. Martin, X. García-Fernández, A. Gómez, M. del Carmen Martinez Jimenez, E. Bouza Santiago, P. Munoz, P. Escribano, J. Guinea Ortega; Poster P0170

  • Comparison of the MICs obtained by Etest and EUCAST methods for amphotericin B, itraconazole, posaconazole, voriconazole and isavuconazole against clinical isolates of Aspergillus fumigatus - J. Guitard, L. Verdurme, Y. Senghor, M. E. Bougnoux, A. Fekkar, F. Botterel, E. Dannaoui, C. Hennequin; Poster P0175

  • Isavuconazole MICs distribution of 20 yeast species involved in human invasive infections - M. Desnos-Ollivier, A. Boullié, O. Lortholary, F. Dromer; Poster P0296

  • In vitro pharmacodynamics of isavuconazole, voriconazole, and posaconazole against agents of aspergillosis, mucormycosis, phaeohyphomycosis, fusariosis, and scedosporiosis. - R. Lewis, N. Beyda, N. Albert, D. P. Kontoyiannis; Poster P0297

  • Real life use of isavuconazole - F. Vuotto, B.  Hennart, S. Loridant, F. Loeuillet, M. C. Chopin, B. Sendid, S. Alfandari, K. Faure ; Poster P0298

  • The cost of treating invasive mould disease with isavuconazole compared with liposomal amphotericin B followed by posaconazole in France - E. Bagshaw, B. Salaun, M. Blackney, J. Posthumus, D. Kuessner; Poster P0303

  • Resistance screening of commonly used antimycotics in rare yeast - A. Pérez Hansen, C. Lass-Flörl, M. Lackner; Poster P0306

  • Isavuconazole shortens the QTc interval - S. Mellinghoff, M. Bassetti, D. Dörfel, S. Hagel, N. Lehners, A. Plis, E. Schalk, A. Vena, O. A. Cornely; Poster P0308A


Isavuconazole at ECCMID 2018  (continued)

Saturday, 21 April 2018 - 15:30 - 16:30 CEST, Paper Poster Arena

  • Antifungal susceptibility of Spanish Candida auris isolates determined by Etest and Sensititre YeastOne - A. Ruiz, M. Fernandez, E. Canton, M. Garrido Jareño, P. Ramirez, J. L. López-Hontangas, J. P. Garcia; Poster 0312

  • Septic metastatic complications after Candida auris candidaemia in the first Spanish outbreak setting - M. Tasias, E. Calabuig, M. Montero, F. Blanes, J. Fernandez, A. Ruiz, I. Castro, A. Aleixandre, J. Mollar, J. Pemán, M. Slavert;
    Poster P0315

Sunday, 22 April 2018 - 13:30 - 14:30 CEST, Paper Poster Arena

  • Evaluation of gradient strip for antifungal susceptibility testing of isavuconazole and comparators against Mucorales - P. Vidal, E. Dannaoui; Poster P1243

Monday, 23 April 2018 - 14:30 - 15:30 CEST, ePoster Arena 1

  • Identification of an isavuconazole dosing regimen for children aged 2-17 years - A. Desai, W. Hope, M. Neely, C. Lademacher, L. Kovanda; ePoster, oral pres. O0795

Tuesday, 24 April 2018; 14:30 - 15:00 CEST, Hall G

  • Pro/con debate: Isavuconazole (not amphotericin B) as primary treatment for mucormycosis - O. A. Cornely; Symposium S1070 / Amphotericin B (not isavuconazole) as primary treatment for mucormycosis - F. Lanternier; Symposium S1071


Ceftobiprole at ECCMID 2018

Saturday, 21 April to Tuesday, 24 April 2018, ePoster terminals

  • Activity of ceftobiprole and comparators against a collection of teicoplanin- and/or linezolid-resistant coagulase-negative staphylococci isolated from bloodstream infections - M. Coppi, A. Antonelli, G. Baldi, L. Mosconi, A. Santerre Henriksen, F. Arena, T. Giani, G. M.  Rossolini; ePoster E0003

  • Activity of ceftobiprole and comparators against European respiratory tract isolates of MSSA and MRSA from 2016 - I. Morrissey, S. De Angelis, S. Magnet, S. Hawser, A. Santerre-Henriksen; ePoster E0006

Saturday, 21 April 2018; 15:30 - 16:30 CEST, Paper Poster Arena

  • Ceftobiprole versus vancomycin in treatment of methicillin-resistant Staphylococcus aureus (MRSA) meningitis in an experimental rabbit model - S. Mermer, E. Bolat, T. Turhan, S. Aydemir, H. Sipahi, O. R. Sipahi; Poster P0263

Monday, 23 April 2018; 13:30 - 14:30 CEST, Paper Poster Arena

  • In vitro susceptibility testing of cerufoxime, cefixime, cefpodoxime, cefotaxime, ceftaroline, ceftobiprole, linezolid and tedizolid against isolates of Nocardia by using the E-test method - E. Bergeron, F. Vautrin, T.  Durand, F.  Laurent, V. Rodriguez-Nava; Poster P1841

  • In vitro activity of tedizolid, dalbavancin and ceftobiprole against Clostridium difficile - D. Binyamin, O. Nitzan, M. Azrad, Z. Hamo, O. Koren, A. Peretz; P1844


Ceftobiprole at ECCMID 2018 (continued)

Tuesday, 24 April 2018; 12:30 - 13:30 CEST, Paper Poster Arena

  • In vivo assessment of ceftobiprole versus daptomycin in a murine model of Staphylococcus aureus bacteremia: antimicrobial activity and impact on host inflammatory response - L. Bouard, J. Caillon, V. Le Mabecque, E. Thomas, K. Asehnoune, C. Jacqueline; Poster P2025

  • Epidemiology and ceftobiprole susceptibility of European Enterobacteriaceae and Gram-positive clinical isolates from different infection sources collected in 2016 - S. Hawser, S. De Angelis, S. Magnet, I. Morrissey, A. Santerre-Henriksen; Poster P2441

  • Bactericidal and synergistic activity of ceftobiprole combined with different antibiotics against selected Gram-positive isolates - F. Campanile, D. Bongiorno, C. Pulitano, S. Stefani; Poster P2498

For further information please visit www.eccmid.org.

1   Cresemba US prescribing information [Accessed: April 19, 2018]
2   European Public Assessment Report (EPAR) Cresemba: http://www.ema.europa.eu [Accessed: April 19, 2018]
3   Full indication in: Swissmedic-approved information for healthcare professionals as of August 2017
4   U.K. Summary of Product Characteristics (SPC) Zevtera: http://www.mhra.gov.uk/ [Accessed: April 19, 2018]


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