Director of Translational Research

Anjarium is a privately held, early-stage biotechnology company focused on creating a new class of non-viral gene therapies to deliver more predictable, enduring, and inclusionary ways to tackle genetic disease throughout a patient’s lifetime. The Company’s versatile platform aims to leverage breakthrough science and expertise at the interface of genetic medicine, synthetic biology and nanoparticle engineering to generate a pipeline of advanced gene therapies with unique competitive advantages over current viral-vector based gene therapies.  We are backed by leading international and strategic investors Abingworth, Gimv, Omega Funds, Pfizer Ventures and Surveyor Capital (a Citadel company).

Currently headquartered at Biotechnopark in Zurich, Switzerland, we are rapidly expanding our teamand are looking for talented and creative individuals, driven by patient outcomes, to join us. Our team is passionate about building a new generation of durable genetic medicines for life-threatening diseases while pushing forward the frontiers of gene therapy.

About the Role:
We are seeking a Director of Translational Research to lead our in vivo and translational efforts, playing an important role in developing and executing Anjarium’s translational development strategy. Responsibilities will include driving scientific research to identify, evaluate, and characterize disease relevant in vivo assays and other fluid / tissue biomarkers to provide efficacy and pharmacodynamic endpoints in preclinical and clinical settings. A background in nonclinical development for gene and/or cell therapies is highly desirable and a proven ability to advance novel therapeutic approaches into and through the clinical development is essential.

Key Responsibilities

• Provide strategic, scientific, and managerial leadership to drive the in vivo and translational scientific strategy
• Develop in vivo and biochemical assays to evaluate efficacy, PK/PD relationships, and novel biomarkers to characterize lead constructs for potential therapeutic activity and efficacy
• Lead in coordination and preparation of study reports, regulatory filings and project presentations
• Communicate, collaborate, and coordinate effectively with cross-functional teams
  Prepare, review and deliver high quality scientific presentations for internal/external use.

Qualifications

• Ph.D. or equivalent degree in biomedical sciences, preferably with focus on translational research, and +10 years of experience, with at least +7 years in biotech / pharma
• A strong track record of success in delivering clinical candidates
  Broad background in all aspects of drug discovery, with working knowledge of in vivo pharmacology, biomarker identification and translational research, ADME/PK, and in vitro pharmacology
• Demonstrated creativity and novel approaches to solving scientific problems
• Experience in Gene and/or cell therapies highly desirable
• Experience of managing and delivering high quality studies through CROs and academic collaborators; demonstrated ability to negotiate contracts, develop study protocols and on-time delivery of study reports supporting development candidate nomination and regulatory submissions
• Willing to work hands-on in a very small team with limited internal resources

Submission of unsolicited resumes in advance of an agreement between Anjarium and any external staffing agency or recruiter does not create any implied obligation on the part of Anjarium Biosciences AG.
External staffing agencies or recruiters are requested to not contact Anjarium employees or members of the Board of Directors directly in any attempt to present candidates.

Anjarium Biosciences AG will not accept unsolicited resumes from any source other than candidates themselves for either current or future positions.