GeNeuro develops a new approach to the treatment of autoimmune diseases, including multiple sclerosis (MS) and Type 1 Diabetes (T1D) associated with pathogenic proteins expressed by human endogenous retroviruses (HERV), viral genes that account for 8% of human DNA.
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GeNeuro has developed temelimab, a humanized monoclonal antibody targeting pHERV-W Env. Temelimab has proven in the Phase II CHANGE-MS 270-patient trial, and in its ANGEL-MS extension, to have a coherent impact across all key markers associated with disease progression in multiple sclerosis.
