Job description

Research Associate Proteomics – Basel

Monte Rosa Therapeutics seeks to recruit a highly motivated research associate in proteomics with drug discovery experience to join its growing proteomics global team. This is an exciting opportunity to join a team responsible for the characterization of novel small molecule glue-based degraders to support Monte Rosa’s growing pipeline.
The successful candidate will be responsible for independently conducting own experiments from cell culture, sample preparation, LC-MS acquisition, to data analysis, interpretation, and presentation of the proteomics results. We are looking for a candidate with strong technical and organizational skills, and a strong collaborative spirit.

Principal Duties and Responsibilities:
• Perform mass spectrometry/quantitative proteomics experiments with the use of nano LC-MS (Thermo Fisher) and proteomics bioinformatics software
• Implement new innovative technologies/methodologies that may enhance proteomic workflows, in particular automation solutions for proteomics sample preparation workflows
• Prepare biological samples for proteomics analysis and execute protein biochemical techniques (SDS page, Western blots, BCA, LC peptide fractionations)
• Work independently with minimal supervision to design, execute advanced experiments, analyze, interpret and communicate data in project team meetings
• Be responsible for lab infrastructure, prepare and maintain laboratory reagents and stocks

Job Qualifications:
• BSc and/or MSc in analytical chemistry, biochemistry or related field
• At least 2 years’ experience in protein mass spectrometry/proteomics in Pharma, Biotech or equivalent
• Hands-on experience with LC-MS instrumentation (Thermo Fisher)
• Experience in culturing mammalian cells and sterile techniques is desirable
• Experience in protein post-translational modification analysis, protein-protein-interaction analysis, and targeted mass spectrometry analysis would be a plus
• Critical and independent thinking with strong analytical and problem-solving skills
• Highly motivated, strong scientific curiosity and interest in drug discovery
• Excellent oral and written communication skills to work in a collaborative, matrix team

Interested Candidates may apply by Sending CV to

Monte Rosa Therapeutics rational approach in targeting disease-causing proteins for degradation will deliver pioneering therapies for cancer and other diseases. Delivering this new generation of treatments to the patients requires a conceptual change. Monte Rosa recognizes this urgent need and is missioned to develop innovative protein degraders as a solution. Combining deep knowledge, insight and leading-edge science, our integrated engine is built for that purpose.


Basel, Switzerland

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